{"id":26246,"date":"2023-10-19T00:46:00","date_gmt":"2023-10-18T17:46:00","guid":{"rendered":"https:\/\/www.prnasia.com\/asia-story\/archive\/4241543_VI41543_11"},"modified":"2023-10-19T00:46:00","modified_gmt":"2023-10-18T17:46:00","slug":"currax-pharmaceuticals-mot-nghien-cuu-bang-chung-thuc-te-lon-va-dai-han-cho-thay-contrner-mysimba-khong-lam-tang-rui-ro-bien-co-tim-mach-lon","status":"publish","type":"post","link":"https:\/\/saigonbiz.com\/vn\/currax-pharmaceuticals-mot-nghien-cuu-bang-chung-thuc-te-lon-va-dai-han-cho-thay-contrner-mysimba-khong-lam-tang-rui-ro-bien-co-tim-mach-lon\/","title":{"rendered":"Currax Pharmaceuticals: m\u1ed9t nghi\u00ean c\u1ee9u b\u1eb1ng ch\u1ee9ng th\u1ef1c t\u1ebf l\u1edbn v\u00e0 d\u00e0i h\u1ea1n cho th\u1ea5y Contrner\u00ae\/MySimba\u00ae kh\u00f4ng l\u00e0m t\u0103ng r\u1ee7i ro bi\u1ebfn c\u1ed1 tim m\u1ea1ch l\u1edbn"},"content":{"rendered":"<table name=\"logo_release\" border=\"0\" cellspacing=\"10\" cellpadding=\"5\" align=\"right\">\n<tbody>\n<tr>\n<td><img decoding=\"async\" src=\"https:\/\/saigonbiz.com.vn\/wp-content\/uploads\/2023\/10\/currax-pharmaceuticals-mot-nghien-cuu-bang-chung-thuc-te-lon-va-dai-han-cho-thay-contrner-mysimba-khong-lam-tang-rui-ro-bien-co-tim-mach-lon.jpg\" border=\"0\" alt title=\"logo\" hspace=\"0\" vspace=\"0\" width=\"118\"><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><span class=\"legendSpanClass\"><span class=\"xn-location\">BRENTWOOD, Tennessee<\/span><\/span>, <span class=\"legendSpanClass\">ng\u00e0y 18 th\u00e1ng 10 n\u0103m 2023<\/span> <span> \/PRNewswire\/ &#8212; <\/span><a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=vi&amp;o=3999760-1&amp;h=1634902940&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D3999760-1%26h%3D492594226%26u%3Dhttps%253A%252F%252Fwww.curraxpharma.com%252F%26a%3DCurrax%2BPharmaceuticals%2BLLC&amp;a=Currax+Pharmaceuticals+LLC\" target=\"_blank\" rel=\"nofollow noopener\"><span>Currax Pharmaceuticals LLC<\/span><\/a><span> (&#8220;Currax&#8221;) h\u00f4m nay \u0111\u00e3 c\u00f4ng b\u1ed1 k\u1ebft qu\u1ea3 \u0111\u00e1ng ch\u00fa \u00fd t\u1eeb m\u1ed9t ph\u00e2n t\u00edch k\u1ebft qu\u1ea3 s\u1ee9c kho\u1ebb tim m\u1ea1ch (HOA). Nghi\u00ean c\u1ee9u n\u00e0y \u0111\u00e1nh gi\u00e1 m\u1ee9c \u0111\u1ed9 an to\u00e0n \u0111\u1ed1i v\u1edbi tim m\u1ea1ch c\u1ee7a CONTRAVE\u00ae\/MYSIMBA\u00ae, m\u1ed9t lo\u1ea1i thu\u1ed1c ki\u1ec3m so\u00e1t c\u00e2n n\u1eb7ng. Nghi\u00ean c\u1ee9u th\u1ef1c t\u1ebf \u0111\u00e3 so s\u00e1nh CONTRAVE\u00ae\/MYSIMBA\u00ae v\u1edbi m\u1ed9t s\u1ea3n ph\u1ea9m t\u01b0\u01a1ng t\u1ef1 v\u1edbi m\u1ee5c \u0111\u00edch \u0111o l\u01b0\u1eddng c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch l\u1edbn (MACE). Ph\u00e2n t\u00edch ch\u00ednh bao g\u1ed3m h\u01a1n 24.600 b\u1ec7nh nh\u00e2n v\u1edbi th\u1eddi gian theo d\u00f5i trung b\u00ecnh h\u01a1n 1700 ng\u00e0y.<\/span><\/p>\n<p><span>C\u00e1c nh\u00e0 nghi\u00ean c\u1ee9u kh\u00f4ng t\u00ecm th\u1ea5y b\u1eb1ng ch\u1ee9ng v\u1ec1 r\u1ee7i ro qu\u00e1 m\u1ee9c v\u1ec1 tim m\u1ea1ch v\u00e0 kh\u00f4ng c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t c\u00f3 \u00fd ngh\u0129a v\u1ec1 m\u1eb7t th\u1ed1ng k\u00ea v\u1ec1 MACE gi\u1eefa nh\u00f3m CONTRAVE\u00ae\/MYSIMBA\u00ae v\u00e0 nh\u00f3m so s\u00e1nh. K\u1ebft qu\u1ea3 HOA l\u00e0 nh\u1ea5t qu\u00e1n v\u1edbi b\u1ed1n th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng ng\u1eabu nhi\u00ean tr\u01b0\u1edbc \u0111\u00f3 v\u00e0 tr\u00ean 9 n\u0103m d\u1eef li\u1ec7u gi\u00e1m s\u00e1t an to\u00e0n sau ti\u1ebfp th\u1ecb trong h\u01a1n 600.000 n\u0103m b\u1ec7nh nh\u00e2n s\u1eed d\u1ee5ng s\u1ea3n ph\u1ea9m. Nh\u1eefng k\u1ebft qu\u1ea3 n\u00e0y gi\u00fap hi\u1ec3u nhi\u1ec1u h\u01a1n v\u1ec1 h\u1ed3 s\u01a1 an to\u00e0n tim m\u1ea1ch c\u1ee7a CONTRAVE\u00ae\/MYSIMBA\u00ae.<\/span><\/p>\n<p><span>&#8220;Ch\u00fang t\u00f4i r\u1ea5t vui khi th\u1ea5y k\u1ebft qu\u1ea3 t\u1eeb ph\u00e2n t\u00edch k\u1ebft qu\u1ea3 s\u1ee9c kh\u1ecfe tim m\u1ea1ch n\u00e0y, t\u1ea1i \u0111\u00f3 bao g\u1ed3m vi\u1ec7c theo d\u00f5i l\u00e2u d\u00e0i c\u00e1c b\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c k\u00ea \u0111\u01a1n CONTRAVE\u00ae\/MYSIMBA\u00ae,&#8221; <span class=\"xn-person\">Michael Kyle<\/span>, B\u00e1c s\u0129 y khoa, Gi\u00e1m \u0111\u1ed1c Y t\u1ebf, Ph\u00f3 Ch\u1ee7 t\u1ecbch Cao c\u1ea5p c\u1ee7a Currax cho bi\u1ebft. &#8220;Ch\u00fang t\u00f4i d\u1ef1 \u0111\u1ecbnh chia s\u1ebb to\u00e0n b\u1ed9 b\u00e1o c\u00e1o nghi\u00ean c\u1ee9u v\u1edbi c\u1ea3 C\u1ee5c Qu\u1ea3n l\u00fd Th\u1ef1c ph\u1ea9m v\u00e0 D\u01b0\u1ee3c ph\u1ea9m Hoa K\u1ef3 (FDA) v\u00e0 C\u01a1 quan Y t\u1ebf ch\u00e2u \u00c2u (EMA); v\u00e0 k\u1ebft qu\u1ea3 \u0111\u1ea7y \u0111\u1ee7 c\u1ee7a nghi\u00ean c\u1ee9u HOA s\u1ebd \u0111\u01b0\u1ee3c c\u00f4ng b\u1ed1 trong m\u1ed9t \u1ea5n ph\u1ea9m khoa h\u1ecdc trong t\u01b0\u01a1ng lai g\u1ea7n.&#8221;<\/span><\/p>\n<p><span>&#8220;Ch\u00fang t\u00f4i \u0111\u00e3 b\u1eaft \u0111\u1ea7u nghi\u00ean c\u1ee9u quan tr\u1ecdng v\u1ec1 s\u1ef1 an to\u00e0n n\u00e0y g\u1ea7n hai n\u0103m tr\u01b0\u1edbc v\u1edbi s\u1ef1 h\u1ed7 tr\u1ee3 c\u1ee7a c\u00e1c chuy\u00ean gia h\u00e0ng \u0111\u1ea7u trong l\u0129nh v\u1ef1c ph\u00e2n t\u00edch b\u1eb1ng ch\u1ee9ng tr\u00ean th\u1ef1c t\u1ebf. T\u00f4i h\u00e0i l\u00f2ng v\u1edbi k\u1ebft qu\u1ea3 v\u00e0 \u00fd ngh\u0129a c\u1ee7a n\u00f3 \u0111\u1ed1i v\u1edbi b\u1ec7nh nh\u00e2n d\u00f9ng CONTRAVE\u00ae\/MYSIMBA\u00ae,&#8221; Ch\u1ee7 t\u1ecbch ki\u00eam Gi\u00e1m \u0111\u1ed1c \u0110i\u1ec1u h\u00e0nh Currax, <span class=\"xn-person\">George Hampton<\/span> cho bi\u1ebft.&nbsp;&#8220;T\u00f4i bi\u1ebft \u01a1n t\u1ea5t c\u1ea3 nh\u1eefng ng\u01b0\u1eddi \u0111\u00e3 gi\u00fap \u0111i\u1ec1u n\u00e0y tr\u1edf th\u00e0nh hi\u1ec7n th\u1ef1c. Ngo\u00e0i vi\u1ec7c c\u00f4ng b\u1ed1 nghi\u00ean c\u1ee9u n\u00e0y, v\u00e0 c\u00f9ng v\u1edbi FDA v\u00e0 EMA, ch\u00fang t\u00f4i \u0111ang chu\u1ea9n b\u1ecb b\u1eaft \u0111\u1ea7u m\u1ed9t th\u1eed nghi\u1ec7m l\u1edbn v\u1ec1 k\u1ebft qu\u1ea3 tim m\u1ea1ch v\u00e0o \u0111\u1ea7u n\u0103m 2024.&#8221;<\/span><\/p>\n<p><b><span>Gi\u1edbi thi\u1ec7u v\u1ec1 ph\u00e2n t\u00edch k\u1ebft qu\u1ea3 s\u1ee9c kh\u1ecfe <br \/><\/span><\/b><span>Ph\u00e2n t\u00edch k\u1ebft qu\u1ea3 s\u1ee9c kh\u1ecfe (Health Outcomes Analysis) l\u00e0 m\u1ed9t nghi\u00ean c\u1ee9u b\u1eb1ng ch\u1ee9ng th\u1ef1c t\u1ebf, kh\u00f4ng can thi\u1ec7p nh\u1eb1m \u0111\u00e1nh gi\u00e1 s\u1ef1 an to\u00e0n \u0111\u1ed1i v\u1edbi tim m\u1ea1ch c\u1ee7a CONTRAVE\u00ae\/MYSIMBA\u00ae (&#8220;S\u1ea3n ph\u1ea9m&#8221;) v\u1edbi m\u1ed9t s\u1ea3n ph\u1ea9m so s\u00e1nh (Locaserin). M\u1ee5c ti\u00eau ch\u00ednh c\u1ee7a nghi\u00ean c\u1ee9u n\u00e0y l\u00e0 so s\u00e1nh t\u1ef7 l\u1ec7 g\u1eb7p c\u00e1c bi\u1ebfn c\u1ed1 tim m\u1ea1ch l\u1edbn [MACE] gi\u1eefa nh\u1eefng ng\u01b0\u1eddi b\u1eaft \u0111\u1ea7u d\u00f9ng CONTRAVE\u00ae\/MYSIMBA\u00ae v\u00e0 nh\u1eefng ng\u01b0\u1eddi b\u1eaft \u0111\u1ea7u d\u00f9ng thu\u1ed1c so s\u00e1nh. C\u00e1c ph\u00e2n t\u00edch ch\u00ednh bao g\u1ed3m 12,475 b\u1ec7nh nh\u00e2n \u0111\u00e3 b\u1eaft \u0111\u1ea7u d\u00f9ng CONTRAVE<sup>\u00ae<\/sup>\/MYSIMBA<sup>\u00ae <\/sup>v\u00e0 12,171 b\u1ec7nh nh\u00e2n b\u1eaft \u0111\u1ea7u d\u00f9ng thu\u1ed1c so s\u00e1nh v\u1edbi th\u1eddi gian theo d\u00f5i trung b\u00ecnh l\u00e0 tr\u00ean 1.700 ng\u00e0y. Nh\u00ecn chung, t\u1ef7 l\u1ec7 g\u1eb7p MACE tr\u00ean 1.000 n\u0103m b\u1ec7nh nh\u00e2n trong nh\u00f3m CONTRAVE\u00ae\/MYSIMBA\u00ae l\u00e0 th\u1ea5p h\u01a1n so v\u1edbi nh\u00f3m thu\u1ed1c so s\u00e1nh. K\u1ebft qu\u1ea3 cho th\u1ea5y kh\u00f4ng c\u00f3 s\u1ef1 kh\u00e1c bi\u1ec7t c\u00f3 \u00fd ngh\u0129a v\u1ec1 m\u1eb7t th\u1ed1ng k\u00ea v\u1ec1 t\u1ef7 l\u1ec7 m\u1eafc nh\u1ed3i m\u00e1u c\u01a1 tim c\u1ea5p t\u00ednh kh\u00f4ng g\u00e2y t\u1eed vong (AMI) v\u00e0 \u0111\u1ed9t qu\u1ef5 gi\u1eefa nh\u00f3m CONTRAVE\u00ae\/MYSIMBA\u00ae v\u00e0 nh\u00f3m thu\u1ed1c so s\u00e1nh.<\/span><\/p>\n<p><b><span>Gi\u1edbi thi\u1ec7u v\u1ec1 CONTRAVE\/MYSIMBA<br \/><\/span><\/b><span>CONTRAVE\u00ae, c\u00f2n \u0111\u01b0\u1ee3c ti\u1ebfp th\u1ecb v\u1edbi t\u00ean MYSIMBA\u00ae \u1edf Li\u00ean minh Ch\u00e2u \u00c2u v\u00e0 Khu v\u1ef1c Kinh t\u1ebf Ch\u00e2u \u00c2u, l\u00e0 s\u1ef1 k\u1ebft h\u1ee3p li\u1ec1u c\u1ed1 \u0111\u1ecbnh ph\u00f3ng th\u00edch k\u00e9o d\u00e0i c\u1ee7a naltrexone v\u00e0 bupropion (naltrexone HCL\/bupropion HCL) \u0111\u01b0\u1ee3c ch\u1ec9 \u0111\u1ecbnh l\u00e0m thu\u1ed1c h\u1ed7 tr\u1ee3 cho ch\u1ebf \u0111\u1ed9 \u0103n gi\u1ea3m calo v\u00e0 t\u0103ng c\u01b0\u1eddng ho\u1ea1t \u0111\u1ed9ng th\u1ec3 ch\u1ea5t \u0111\u1ec3 ki\u1ec3m so\u00e1t c\u00e2n n\u1eb7ng m\u00e3n t\u00ednh \u1edf ng\u01b0\u1eddi l\u1edbn c\u00f3 ch\u1ec9 s\u1ed1 kh\u1ed1i c\u01a1 th\u1ec3 ban \u0111\u1ea7u (BMI) t\u1eeb 30 kg\/m<sup>2<\/sup> tr\u1edf l\u00ean (b\u00e9o ph\u00ec) ho\u1eb7c ng\u01b0\u1eddi l\u1edbn c\u00f3 ch\u1ec9 s\u1ed1 BMI t\u1eeb 27 kg\/m<sup>2<\/sup> tr\u1edf l\u00ean (th\u1eeba c\u00e2n) c\u00f3 \u00edt nh\u1ea5t m\u1ed9t v\u1ea5n \u0111\u1ec1 y t\u1ebf li\u00ean quan \u0111\u1ebfn c\u00e2n n\u1eb7ng nh\u01b0 huy\u1ebft \u00e1p cao, cholesterol cao, ho\u1eb7c ti\u1ec3u \u0111\u01b0\u1eddng tu\u00fdp 2.<\/span><\/p>\n<p><span>Logo &#8211; <\/span><a href=\"https:\/\/c212.net\/c\/link\/?t=0&amp;l=vi&amp;o=3999760-1&amp;h=3125759359&amp;u=https%3A%2F%2Fc212.net%2Fc%2Flink%2F%3Ft%3D0%26l%3Den%26o%3D3999760-1%26h%3D2144469431%26u%3Dhttps%253A%252F%252Fmma.prnewswire.com%252Fmedia%252F2250440%252FCurrax_Pharmaceuticals_Logo.jpg%26a%3Dhttps%253A%252F%252Fmma.prnewswire.com%252Fmedia%252F2250440%252FCurrax_Pharmaceuticals_Logo.jpg&amp;a=https%3A%2F%2Fmma.prnewswire.com%2Fmedia%2F2250440%2FCurrax_Pharmaceuticals_Logo.jpg\" target=\"_blank\" rel=\"nofollow noopener\"><span>https:\/\/saigonbiz.com.vn\/wp-content\/uploads\/2023\/10\/currax-pharmaceuticals-mot-nghien-cuu-bang-chung-thuc-te-lon-va-dai-han-cho-thay-contrner-mysimba-khong-lam-tang-rui-ro-bien-co-tim-mach-lon.jpg<\/span><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>BRENTWOOD, Tennessee, ng\u00e0y 18 th\u00e1ng 10 n\u0103m 2023 \/PRNewswire\/ &#8212; Currax Pharmaceuticals LLC (&#8220;Currax&#8221;) h\u00f4m nay \u0111\u00e3 c\u00f4ng b\u1ed1 k\u1ebft qu\u1ea3 \u0111\u00e1ng ch\u00fa \u00fd t\u1eeb m\u1ed9t ph\u00e2n t\u00edch k\u1ebft qu\u1ea3 s\u1ee9c kho\u1ebb tim m\u1ea1ch (HOA). Nghi\u00ean c\u1ee9u n\u00e0y \u0111\u00e1nh gi\u00e1 m\u1ee9c \u0111\u1ed9 an to\u00e0n \u0111\u1ed1i v\u1edbi tim m\u1ea1ch c\u1ee7a CONTRAVE\u00ae\/MYSIMBA\u00ae, m\u1ed9t lo\u1ea1i thu\u1ed1c ki\u1ec3m so\u00e1t [&#8230;]\n","protected":false},"author":4,"featured_media":26247,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[2293],"tags":[],"class_list":["post-26246","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v21.6 (Yoast SEO v27.2) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Currax Pharmaceuticals: m\u1ed9t nghi\u00ean c\u1ee9u b\u1eb1ng ch\u1ee9ng th\u1ef1c t\u1ebf l\u1edbn v\u00e0 d\u00e0i h\u1ea1n cho th\u1ea5y Contrner\u00ae\/MySimba\u00ae kh\u00f4ng 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