{"id":24046,"date":"2023-08-09T19:14:00","date_gmt":"2023-08-09T12:14:00","guid":{"rendered":"https:\/\/www.prnasia.com\/asia-story\/archive\/4177612_VI77612_11"},"modified":"2023-08-09T19:14:00","modified_gmt":"2023-08-09T12:14:00","slug":"ban-cap-nhat-chien-luoc-thang-8-nam-2023-cua-race","status":"publish","type":"post","link":"https:\/\/saigonbiz.com\/vn\/ban-cap-nhat-chien-luoc-thang-8-nam-2023-cua-race\/","title":{"rendered":"B\u1ea3n c\u1eadp nh\u1eadt chi\u1ebfn l\u01b0\u1ee3c th\u00e1ng 8 n\u0103m 2023 c\u1ee7a Race"},"content":{"rendered":"

SYDNEY<\/span>, 09\/08\/2023<\/span> \/PRNewswire\/ — Race Oncology Limited (“Race”) h\u00e2n h\u1ea1nh cung c\u1ea5p m\u1ed9t b\u1ea3n c\u1eadp nh\u1eadt chi\u1ebfn l\u01b0\u1ee3c, bao g\u1ed3m th\u00f4ng tin t\u1ed5ng quan v\u1ec1 s\u1eeda \u0111\u1ed5i trong chi\u1ebfn l\u01b0\u1ee3c doanh nghi\u1ec7p, nh\u1eb1m t\u1ed1i \u01b0u h\u00f3a vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c ngu\u1ed3n l\u1ef1c hi\u1ec7n c\u00f3, \u0111\u1ed3ng th\u1eddi th\u00fac \u0111\u1ea9y ti\u1ec1m n\u0103ng h\u1ee3p t\u00e1c v\u00e0 \u0111\u1ed1i t\u00e1c th\u01b0\u01a1ng m\u1ea1i c\u1ee7a bisantrene.<\/p>\n

Ph\u00e1t tri\u1ec3n chi\u1ebfn l\u01b0\u1ee3c c\u00f4ng ty<\/b><\/p>\n

Chi\u1ebfn l\u01b0\u1ee3c m\u1edbi c\u1ee7a Race \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf nh\u1eb1m t\u1ed1i \u0111a h\u00f3a gi\u00e1 tr\u1ecb v\u1ed1n c\u00f3 c\u1ee7a bisantrene:<\/p>\n

Ch\u1ed1ng ung th\u01b0 + b\u1ea3o v\u1ec7 tim m\u1ea1ch<\/b><\/p>\n

Tr\u1ecdng t\u00e2m c\u1ed1t l\u00f5i c\u1ee7a Race l\u00e0 t\u00e1c \u0111\u1ed9ng \u0111\u1ebfn k\u1ebft qu\u1ea3 \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u00e0 gi\u1ea3i quy\u1ebft c\u00e1c th\u00e1ch th\u1ee9c v\u1ec1 \u0111\u1ed9c t\u00ednh c\u1ee7a h\u00f3a tr\u1ecb \u0111\u1ed1i v\u1edbi tim m\u1ea1ch. C\u00e1c nghi\u00ean c\u1ee9u s\u1ebd t\u1eadn d\u1ee5ng c\u01a1 ch\u1ebf \u0111\u1ed9c \u0111\u00e1o c\u1ee7a bisantrene trong \u0111i\u1ec1u tr\u1ecb ung th\u01b0 v\u00fa di c\u0103n (mBC) v\u00e0 b\u1ea1ch c\u1ea7u c\u1ea5p t\u00ednh d\u00f2ng t\u1ee7y (AML), c\u1ea3 hai nh\u00f3m b\u1ec7nh nh\u00e2n ung th\u01b0 c\u00f3 nhu c\u1ea7u ch\u01b0a \u0111\u01b0\u1ee3c \u0111\u00e1p \u1ee9ng cao, m\u1edf \u0111\u01b0\u1eddng cho h\u00e0ng lo\u1ea1t ch\u1ec9 \u0111\u1ecbnh trong t\u01b0\u01a1ng lai.<\/i><\/p>\n

Ung th\u01b0 v\u00fa di c\u0103n (mBC)<\/u> <\/p>\n

Nh\u00f3m b\u1ec7nh nh\u00e2n mBC s\u1ebd h\u01b0\u1edfng nhi\u1ec1u l\u1ee3i \u00edch t\u1eeb m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb c\u00f3 th\u1ec3 \u0111em l\u1ea1i kh\u1ea3 n\u0103ng ch\u1ed1ng ung th\u01b0 v\u00e0 b\u1ea3o v\u1ec7 tim m\u1ea1ch b\u1eb1ng c\u00e1ch cho ph\u00e9p cung c\u1ea5p nhi\u1ec1u li\u1ec1u h\u01a1n v\u1edbi h\u1ed3 s\u01a1 an to\u00e0n \u0111\u01b0\u1ee3c c\u1ea3i thi\u1ec7n.<\/p>\n

mBC \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh l\u00e0 ch\u1ec9 \u0111\u1ecbnh h\u00e0ng \u0111\u1ea7u cho bisantrene do c\u0103n b\u1ec7nh n\u00e0y mang l\u1ea1i cho Race c\u01a1 h\u1ed9i gi\u1ea3i quy\u1ebft nhu c\u1ea7u cao ch\u01b0a \u0111\u01b0\u1ee3c \u0111\u00e1p \u1ee9ng r\u00f5 r\u00e0ng n\u00e0y c\u1ee7a b\u1ec7nh nh\u00e2n v\u00e0, v\u1edbi kho\u1ea3ng 36.000 b\u1ec7nh nh\u00e2n m\u1eafc mBC \u1edf Hoa K\u1ef3 m\u1ed7i n\u0103m, \u0111\u00e2y l\u00e0 m\u1ed9t c\u01a1 h\u1ed9i th\u01b0\u01a1ng m\u1ea1i l\u1edbn.<\/p>\n

Race d\u1ef1 \u0111\u1ecbnh \u0111\u01b0a c\u00f4ng th\u1ee9c bisantrene RC220 v\u00e0o th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng giai \u0111o\u1ea1n 1\/2 k\u1ebft h\u1ee3p v\u1edbi anthracycline doxorubicin, lo\u1ea1i thu\u1ed1c h\u00f3a tr\u1ecb \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng r\u1ed9ng r\u00e3i nh\u1ea5t trong \u0111i\u1ec1u tr\u1ecb mBC. Th\u1eed nghi\u1ec7m s\u1ebd \u0111i v\u00e0o ho\u1ea1t \u0111\u1ed9ng khi c\u00f3 s\u1eb5n GMP RC220 v\u00e0 sau khi ho\u00e0n th\u00e0nh nghi\u00ean c\u1ee9u \u0111\u1ed9c t\u00ednh, \u0111\u1ec7 tr\u00ecnh \u0111\u1ea1o \u0111\u1ee9c v\u00e0 ph\u00ea duy\u1ec7t t\u1eeb c\u01a1 quan qu\u1ea3n l\u00fd. Khung th\u1eddi gian d\u1ef1 ki\u1ebfn \u0111\u1ec3 b\u1eaft \u0111\u1ea7u th\u1eed nghi\u1ec7m l\u00e0 qu\u00fd 3 d\u01b0\u01a1ng l\u1ecbch n\u0103m 2024.<\/p>\n

B\u1ec7nh b\u1ea1ch c\u1ea7u c\u1ea5p t\u00ednh d\u00f2ng t\u1ee7y (AML)<\/u> <\/p>\n

Ch\u01b0\u01a1ng tr\u00ecnh AML v\u1eabn l\u00e0 m\u1ed9t ph\u1ea7n quan tr\u1ecdng trong chi\u1ebfn l\u01b0\u1ee3c c\u1ee7a Race v\u00ec v\u1eabn c\u1ea7n m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb m\u1edbi gi\u00fap c\u1ea3i thi\u1ec7n c\u00e1c l\u1ef1a ch\u1ecdn \u0111i\u1ec1u tr\u1ecb ung th\u01b0 hi\u1ec7n t\u1ea1i, \u0111\u1ed3ng th\u1eddi h\u1ea1n ch\u1ebf \u0111\u1ed9c t\u00ednh cho kho\u1ea3ng 16.000 b\u1ec7nh nh\u00e2n AML t\u1ea1i Hoa K\u1ef3 m\u1ed7i n\u0103m, nh\u1eefng ng\u01b0\u1eddi \u0111\u01b0\u1ee3c \u0111\u00e1nh gi\u00e1 l\u00e0 kh\u00f4ng ph\u00f9 h\u1ee3p v\u1edbi c\u00e1c ph\u01b0\u01a1ng ph\u00e1p \u0111i\u1ec1u tr\u1ecb kh\u00e1c.<\/p>\n

Race d\u1ef1 \u0111\u1ecbnh \u0111\u01b0a bisantrene v\u00e0o th\u1eed nghi\u1ec7m l\u00e2m s\u00e0ng giai \u0111o\u1ea1n 1b<\/span>\/2a, trong \u0111\u00f3 c\u00f4ng th\u1ee9c n\u00e0y s\u1ebd \u0111\u01b0\u1ee3c nghi\u00ean c\u1ee9u k\u1ebft h\u1ee3p v\u1edbi decitabine\/cedazuridine d\u1ea1ng u\u1ed1ng trong c\u00e1c nghi\u00ean c\u1ee9u t\u0103ng li\u1ec1u, sau \u0111\u00f3 l\u00e0 k\u1ebft h\u1ee3p c\u1ea3 ba ch\u1ea5t v\u1edbi li\u1ec7u ph\u00e1p ti\u00eau chu\u1ea9n hi\u1ec7n c\u00f3. Giai \u0111o\u1ea1n ban \u0111\u1ea7u s\u1ebd cung c\u1ea5p qu\u00e1 tr\u00ecnh chuy\u1ec3n \u0111\u1ed5i t\u1eeb c\u00f4ng th\u1ee9c RC110 (\u0111\u01b0\u1ee3c ti\u00eam v\u00e0o t\u0129nh m\u1ea1ch trung t\u00e2m) ban \u0111\u1ea7u sang RC220. K\u1ebf ho\u1ea1ch th\u1eed nghi\u1ec7m d\u1ef1 ki\u1ebfn s\u1ebd b\u1eaft \u0111\u1ea7u v\u00e0o cu\u1ed1i qu\u00fd 4 d\u01b0\u01a1ng l\u1ecbch n\u0103m 2023, v\u1edbi c\u00e1c giai \u0111o\u1ea1n chuy\u1ec3n ti\u1ebfp t\u1eeb RC110 sang RC220 trong n\u0103m 2024.<\/p>\n

Race tin r\u1eb1ng ch\u01b0\u01a1ng tr\u00ecnh AML mang \u0111\u1ebfn nh\u1eefng c\u01a1 h\u1ed9i to l\u1edbn \u0111\u1ec3 s\u1edbm k\u00fd k\u1ebft m\u1ed1i quan h\u1ec7 h\u1ee3p t\u00e1c v\u1edbi c\u00e1c \u0111\u1ed1i t\u00e1c th\u01b0\u01a1ng m\u1ea1i.<\/p>\n

Kh\u00e1m ph\u00e1<\/b><\/p>\n

Ch\u01b0\u01a1ng tr\u00ecnh kh\u00e1m ph\u00e1 c\u1ee7a ch\u00fang t\u00f4i \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf \u0111\u1ec3 l\u00e0m s\u00e1ng t\u1ecf h\u01a1n c\u01a1 ch\u1ebf t\u00e1c \u0111\u1ed9ng b\u1ea3o v\u1ec7 tim m\u1ea1ch c\u0169ng nh\u01b0 c\u00e1c k\u1ebft qu\u1ea3 t\u1eeb B\u1ec7nh vi\u1ec7n Ung th\u01b0 City Of Hope r\u1eb1ng bisantrene l\u00e0 ch\u1ea5t \u1ee9c ch\u1ebf FTO m\u1ea1nh nh\u1ea5t. Ph\u00e1t hi\u1ec7n n\u00e0y g\u1ee3i \u00fd m\u1ed9t l\u1ef1a ch\u1ecdn cung c\u1ea5p li\u1ec7u ph\u00e1p nh\u1eafm m\u1ee5c ti\u00eau cho b\u1ec7nh nh\u00e2n ph\u00f9 h\u1ee3p, \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh l\u00e0 c\u00f3 bi\u1ec3u hi\u1ec7n qu\u00e1 m\u1ee9c c\u1ee7a FTO.<\/i><\/p>\n

Ch\u01b0\u01a1ng tr\u00ecnh kh\u00e1m ph\u00e1 n\u00e0y s\u1ebd:<\/p>\n

\u00b7  Ti\u1ebfp t\u1ee5c x\u00e2y d\u1ef1ng ki\u1ebfn th\u1ee9c v\u1ec1 c\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng \u0111\u1ed9c \u0111\u00e1o c\u1ee7a bisantrene cho ph\u00e9p gi\u1ea3m \u0111\u1ed9c t\u00ednh \u0111\u1ed1i v\u1edbi tim m\u1ea1ch v\u00e0 li\u00ean quan \u0111\u1ebfn b\u1ea3o v\u1ec7 tim m\u1ea1ch khi k\u1ebft h\u1ee3p v\u1edbi anthracyclines<\/p>\n

\u00b7  Gi\u00fap x\u00e1c \u0111\u1ecbnh l\u1ee3i \u00edch l\u00e2m s\u00e0ng ri\u00eang l\u1ebb c\u1ee7a anthracenes so v\u1edbi anthracycline nh\u01b0 thu\u1ed1c h\u00f3a tr\u1ecb doxorubicin<\/p>\n

\u00b7  T\u0103ng c\u01b0\u1eddng kh\u00e1m ph\u00e1 FTO th\u00f4ng qua li\u00ean minh City of Hope<\/p>\n

\u00b7  Ti\u1ebfp t\u1ee5c theo \u0111u\u1ed5i ch\u01b0\u01a1ng tr\u00ecnh kh\u00e1m ph\u00e1 ch\u1ea5t \u1ee9c ch\u1ebf FTO v\u1edbi \u0110\u1ea1i h\u1ecdc Monash<\/p>\n

\u00b7  Hi\u1ec3u r\u00f5 c\u01a1 ch\u1ebf ho\u1ea1t \u0111\u1ed9ng trong l\u1ed9 tr\u00ecnh m6A<\/p>\n

\u00b7  Ph\u00e1t tri\u1ec3n x\u00e9t nghi\u1ec7m d\u1ea5u \u1ea5n sinh h\u1ecdc c\u00f3 th\u1ec3 s\u1eed d\u1ee5ng trong ph\u00f2ng kh\u00e1m<\/p>\n

Bisantrene m\u1edbi<\/b><\/p>\n

C\u00e1c ho\u1ea1t \u0111\u1ed9ng \u0111\u01b0\u1ee3c ti\u1ebfn h\u00e0nh trong khu\u00f4n kh\u1ed5 ch\u01b0\u01a1ng tr\u00ecnh n\u00e0y \u0111\u01b0\u1ee3c thi\u1ebft k\u1ebf v\u1edbi m\u1ee5c \u0111\u00edch t\u0103ng c\u01b0\u1eddng quy\u1ec1n s\u1edf h\u1eefu tr\u00ed tu\u1ec7 cho bisantrene c\u0169ng nh\u01b0 ph\u00e1t tri\u1ec3n th\u1ebf h\u1ec7 ti\u1ebfp theo c\u1ee7a bisantrene nh\u1eb1m c\u1ea3i thi\u1ec7n k\u1ebft qu\u1ea3 v\u00e0 tr\u1ea3i nghi\u1ec7m c\u1ee7a b\u1ec7nh nh\u00e2n.<\/i> <\/p>\n

Ch\u01b0\u01a1ng tr\u00ecnh n\u00e0y s\u1ebd:<\/p>\n

\u00b7  X\u00e2y d\u1ef1ng v\u00e0 t\u1eadn d\u1ee5ng n\u1ec1n t\u1ea3ng t\u1eeb RC110, \u0111\u01b0a RC220 v\u00e0o ph\u00f2ng kh\u00e1m<\/b><\/p>\n

\u00b7  Ph\u00e1t tri\u1ec3n bisantrene th\u1ebf h\u1ec7 ti\u1ebfp theo <\/b>m\u1edf r\u1ed9ng c\u00e1c ch\u1ec9 \u0111\u1ecbnh \u0111i\u1ec1u tr\u1ecb, t\u0103ng c\u01b0\u1eddng quy\u1ec1n s\u1edf h\u1eefu tr\u00ed tu\u1ec7 v\u00e0 t\u1ed1i \u01b0u h\u00f3a l\u1ef1a ch\u1ecdn \u0111\u1ed1i t\u00e1c v\u1edbi kh\u1ea3 n\u0103ng gia t\u0103ng tu\u1ed5i th\u1ecd t\u1ed5ng th\u1ec3 c\u1ee7a bisantrene<\/p>\n

Ch\u1ec9 \u0111\u1ecbnh b\u1ed5 sung ti\u1ebfp theo<\/b><\/p>\n

Tr\u1ecdng t\u00e2m c\u1ee7a Race \u0111\u1eb7t v\u00e0o mBC v\u00e0 AML \u0111\u00e3 khi\u1ebfn C\u00f4ng ty ph\u00e2n lo\u1ea1i c\u00e1c ch\u1ec9 \u0111\u1ecbnh \u0111\u01b0\u1ee3c \u0111i\u1ec1u tra kh\u00e1c m\u00e0 c\u00f4ng ty \u0111\u00e3 s\u1ea3n xu\u1ea5t d\u1eef li\u1ec7u tri\u1ec3n v\u1ecdng \u0111\u01b0\u1ee3c g\u1ecdi l\u00e0 “c\u00e1c ch\u1ec9 \u0111\u1ecbnh ti\u1ebfp theo”. Nh\u1eefng l\u0129nh v\u1ef1c b\u1ec7nh n\u00e0y bao g\u1ed3m ung th\u01b0 h\u1eafc t\u1ed1 da, sarcoma m\u00f4 m\u1ec1m, ung th\u01b0 t\u1ebf b\u00e0o th\u1eadn, ung th\u01b0 ph\u1ed5i t\u1ebf b\u00e0o nh\u1ecf v\u00e0 ung th\u01b0 ph\u1ed5i.<\/p>\n

Chi\u1ebfn l\u01b0\u1ee3c th\u01b0\u01a1ng m\u1ea1i h\u00f3a<\/b><\/p>\n

Race \u0111\u00e3 s\u1eb5n s\u00e0ng v\u1ec1 m\u1eb7t th\u01b0\u01a1ng m\u1ea1i v\u00e0 \u0111\u01b0\u1ee3c \u0111\u1ecbnh v\u1ecb \u0111\u1ec3 tham gia v\u00e0o c\u00e1c cu\u1ed9c \u0111\u1ed1i tho\u1ea1i d\u01b0\u1ee3c ph\u1ea9m sinh h\u1ecdc qu\u1ed1c t\u1ebf, t\u1ea1o \u0111i\u1ec1u ki\u1ec7n cho c\u00e1c c\u01a1 h\u1ed9i h\u1ee3p t\u00e1c \u0111\u1ed1i t\u00e1c. Race tin r\u1eb1ng ch\u01b0\u01a1ng tr\u00ecnh l\u00e2m s\u00e0ng c\u1ee7a h\u1ecd s\u1ebd n\u00e2ng cao v\u00e0 mang m\u1ed9t c\u01a1 h\u1ed9i th\u01b0\u01a1ng m\u1ea1i \u0111\u1ed9c \u0111\u00e1o c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n b\u1edfi m\u1ed9t c\u00f4ng ty d\u01b0\u1ee3c ph\u1ea9m ph\u00f9 h\u1ee3p tr\u00ean th\u1ecb tr\u01b0\u1eddng.<\/p>\n

Race duy tr\u00ec m\u1ed9t ngu\u1ed3n d\u1ef1 tr\u1eef ti\u1ec1n m\u1eb7t v\u1eefng ch\u1eafc. C\u1ea3 nghi\u00ean c\u1ee9u AML Giai \u0111o\u1ea1n 1b<\/span>\/2a v\u00e0 c\u00e1c ch\u01b0\u01a1ng tr\u00ecnh ti\u1ec1n l\u00e2m s\u00e0ng cam k\u1ebft \u0111\u1ec1u \u0111\u01b0\u1ee3c t\u00e0i tr\u1ee3 \u0111\u1ea7y \u0111\u1ee7. Race \u0111ang \u0111i\u1ec1u tra nhi\u1ec1u ph\u01b0\u01a1ng th\u1ee9c t\u00e0i tr\u1ee3 cho nghi\u00ean c\u1ee9u v\u1ec1 mBC d\u1ef1 ki\u1ebfn b\u1eaft \u0111\u1ea7u v\u00e0o cu\u1ed1i n\u0103m 2024. <\/p>\n

B\u1ea1n c\u00f3 th\u1ec3 t\u1ea3i xu\u1ed1ng B\u1ea3n c\u1eadp nh\u1eadt Chi\u1ebfn l\u01b0\u1ee3c v\u00e0 B\u1ed9 t\u00e0i li\u1ec7u Chi\u1ebfn l\u01b0\u1ee3c t\u1ea1i \u0111\u00e2y.<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

SYDNEY, 09\/08\/2023 \/PRNewswire\/ — Race Oncology Limited (“Race”) h\u00e2n h\u1ea1nh cung c\u1ea5p m\u1ed9t b\u1ea3n c\u1eadp nh\u1eadt chi\u1ebfn l\u01b0\u1ee3c, bao g\u1ed3m th\u00f4ng tin t\u1ed5ng quan v\u1ec1 s\u1eeda \u0111\u1ed5i trong chi\u1ebfn l\u01b0\u1ee3c doanh nghi\u1ec7p, nh\u1eb1m t\u1ed1i \u01b0u h\u00f3a vi\u1ec7c s\u1eed d\u1ee5ng c\u00e1c ngu\u1ed3n l\u1ef1c hi\u1ec7n c\u00f3, \u0111\u1ed3ng th\u1eddi th\u00fac \u0111\u1ea9y ti\u1ec1m n\u0103ng h\u1ee3p t\u00e1c v\u00e0 \u0111\u1ed1i t\u00e1c […]\n","protected":false},"author":4,"featured_media":50415,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"footnotes":""},"categories":[2293],"tags":[],"class_list":["post-24046","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-pr-newswire"],"yoast_head":"\nB\u1ea3n c\u1eadp nh\u1eadt chi\u1ebfn 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